Wed 25 Mar, 2009
Acetyl-L-carnitine is a dietary supplement used to improve memory, such as in Alzheimer’s disease. Acetyl-L-carnitine may improve depression. Other uses for acetyl-L-carnitine include the treatment of Parkinson’s disease, stroke, and Peyronie’s disease.
L-carnitine is a derivative of the amino acid, lysine. Its name is derived from the fact that it was first isolated from meat (carnus) in 1905. Only the L-isomer of carnitine is biologically active. L-carnitine appeared to act as a vitamin in the mealworm (Tenebrio molitor), and was therefore termed vitamin BT. Vitamin BT, however, is actually a misnomer because humans and other higher organisms can synthesize L-carnitine. Under certain conditions, the demand for L-carnitine may exceed an individual’s capacity to synthesize it, making it a conditionally essential micronutrient.
Acetyl L-Carnitine and carnitine play several important roles in the human body. These nutrients shuttle acetyl groups and fatty acids into mitochondria for energy production. Without carnitine, fatty acids cannot easily enter into mitochondria. The acetyl group of acetyl l carnitine is used to form acetyl-CoA, the most important intermediary in the generation of energy from amino acids, fats, and carbohydrates.
Therefore, acetyl l carnitine serves as an energy reservoir of acetyl groups and both acetyl l-carnitine and carnitine help improve energy production. The acetyl group of acetyl l carnitine is also used to make the important brain chemical acetylcholine. Some studies suggest that perhaps acetyl l carnitine can even act as a neurotransmitter itself.
Talk with your doctor, pharmacist, or nurse about how much acetyl-L-carnitine you should take. The amount depends on the strength of the supplement and the reason you are taking it. If you are using this supplement without instructions from your caregiver, follow the directions on the label. Do not take more acetyl-L-carnitine or take it more often than what is written on the directions.
Great supplements like acetyl l-carnitine and l-carnitine are available in capsule, tablet, and powder forms. Look for quality brands like Solaray, Source Naturals, and Kal which are found at your local or internet health food store at discount prices.
*Statements contained herein have not been evaluated by the Food and Drug Administration. Acetyl l-carnitine and l-carniting are not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.
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